Kazakhstan President Kassym-Jomart Tokayev and Uzbekistan President Shavkat Mirziyoyev met in Bukhara to strengthen economic and strategic cooperation.
Bilateral trade reached nearly $5 billion last year, with both sides aiming to double that figure.
The leaders outlined new areas for cooperation, including digital technologies, water management, and environmental protection.
A joint Clean Air initiative was highlighted by Mirziyoyev, aimed at addressing air pollution challenges in major regional border cities.
Tokayev expressed support for deepening cooperation in innovation and digitalisation, as well as backing Uzbekistan's environmental initiatives.
Both governments are now focusing on translating agreements into concrete outcomes, with plans to expand cooperation in energy, industrial supply chains, and the processing of raw materials.
